All patients included in this study were retrieved from the ANGEL (Acute Ischemic Stroke Cooperation Group of Endovascular Treatment) registry, which is a multi-centric, nationwide, prospective registry study launched in June 2015 and terminated in December 2017. Details of the study design have been reported.11 Consecutive AIS patients secondary to large-artery occlusion treated with endovascular methods were selected according to the inclusion and exclusion criteria from the ANGEL registry study.11
All candidates underwent emergency cranial non-contrast CT before treatment. In cases with unknown or prolonged time window (>6 hours), DWI/PWI or CTV/CTP mismatch was introduced for the interventional recanalization. The protocol and data collection of the ANGEL Registry was approved by the ethics committee of Beijing Tiantan Hospital and all other participating centers. This study was conducted in accordance with the Declaration of Helsinki. Written informed consent was provided by all patients or their representatives.
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