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Quality and risk of bias assessment

AB Amy Buchanan-Hughes
AB Anna Bobrowska
CV Cristina Visintin
GA George Attilakos
JM John Marshall
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Pre-specified tools used to assess the quality and risk of bias of each study included in the review were the following: JBI Critical Appraisal Checklist for Studies Reporting Prevalence Data for epidemiological studies [28], Centre for Evidence Based Medicine Prognostic Studies Critical Appraisal Worksheet for prognostic studies [29] and Quality Assessment of Diagnostic Accuracy Studies (QUADAS-2) tool for diagnostic accuracy studies [30]. For the question on management pathways, checklists were pre-specified for randomised controlled trials (RCTs) [31], interventional non-RCTs [32], cohort studies [33] and case-control studies [34]; however, no studies of these designs were identified in the rapid review.

When considering outcomes reported as odds ratios (ORs) or other measures of relative risk, an OR from 0.5 to 2 was considered a weak effect, an OR from 0.2 to 0.5 or 2 to 5 was considered a moderate effect and an OR < 0.2 or > 5 was considered a strong effect.

Copyright and License information: The Author(s) ©2020
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