Predictive Ability of MOI and FWS to Discriminate Between Imported and Local Cases

MR Michelle E Roh
ST Sofonias K Tessema
MM Maxwell Murphy
NN Nomcebo Nhlabathi
NM Nomcebo Mkhonta
SV Sibonakaliso Vilakati
NN Nyasatu Ntshalintshali
MS Manik Saini
GM Gugu Maphalala
AC Anna Chen
JW Jordan Wilheim
LP Lisa Prach
RG Roly Gosling
SK Simon Kunene
MH Michelle S. Hsiang
BG Bryan Greenhouse
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Logistic regression was used to assess whether the addition of MOI and mean FWS to epidemiologically parameterized models would predict whether a case was imported or locally acquired. The base epidemiological model included the following predictors: district of residence, season, case detection method (passive vs reactive surveillance), age, sex, and occupation. Model improvement was tested using the log-likelihood Χ2 statistic and discriminative ability was assessed by the change in the area under the receiver operating characteristic curve.

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