Coronary angiography was performed using the Sones technique with filming of multiple views of each vessel by the same cardiologist. Significant CAD was considered present, when a stenosis of at least 50% of the lumen was found in a major coronary vessel. Moreover, the results of quantitative coronary angiography have also been expressed according to the Gensini scoring system [17]. Gensini score: stenosis <25% was recorded as 1 point, 25–49% was marked as 2 points, 50–74% was noted as 4 points, 75–90% was noted as 8 points, 91–99% was recorded as 16 points, 100% was recorded as 32 points. Factor: LM ×5, LCX opening ×3.5; left anterior descending artery, circumflex artery near, middle and far segments respectively ×2.5, 1.5, 1; right coronary ×1; D1 diagonal branch ×1; D2 diagonal branch ×0.5; left ventricular posterior branch ×1; obtuse marginal branch ×1, right posterior descending branch ×1, posterior collateral ×0.5. Gensini score = Σ (coronary stenosis × lesion factor). Gensini scoring systems were calculated by 2 cardiologists blind to the participants. Then, the mean of 2 measures was calculated. Patients with Gensini score 20 or higher were considered as serious coronary disease [18].
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