An echocardiography core laboratory at the Medical College of Wisconsin reviewed 2D/Doppler echocardiograms performed at each clinical center within 1 year of a subject’s 6th birth date. The echocardiogram was performed at SVR-designated clinical sites when possible, but also could be performed under the supervision of the local primary cardiologist. Core lab procedures for image analysis and data management have been previously described.6,7 Echocardiographic measures are summarized in supplemental Tables 1 and 2. The core lab was blinded to the initial shunt type once the shunt was removed at the Stage II operation for all 14 month, pre-Fontan, and 6-year echocardiograms.
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