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Determination of KIR 2D (L1, L3, L4, S4) and KIR 3DL1 IHC cutoff

YH Yayi He
PB Paul A. Bunn
CZ Caicun Zhou
DC Dan Chan
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All IHC results were independently checked by two pathologists. Staining was evaluated using the H score system [39]. We defined KIR 2D (L1, L3, L4, S4) positivity as an H score greater than 200 for tumor cells and greater than 210 for TILs, respectively. We chose to define KIR 3DL1 positivity on tumor cells and TILs as greater than 200 because that cut off best predicted OS.

Copyright and License information:  ©2016 He et al.
This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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