Experimental Procedure

KV Kristof Vandekerckhove
JP Joseph Panzer
IC Ilse Coomans
AM Annelies Moerman
KG Katya De Groote
HW Hans De Wilde
TB Thierry Bové
KF Katrien François
DW Daniel De Wolf
JB Jan Boone
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An incremental exercise test was performed on an electromagnetically braked cycle ergometer (Ergoline Ergoselect 100K, Bitz, Germany). Following a 3 min warm-up at unloaded cycling, the work rate increased in a linear and continuous way (i.e., ramp exercise). The ramp slope (i.e., the increase in work rate per minute) was individualized and determined by dividing the individual body weight by 4 and rounding off to the closest natural number [0 Watt + (body weight/4) Watt.min–1]. This internally validated protocol leads to an optimal exercise duration of 8 – 12 min in healthy children, with reference values equal to the values of Wasserman et al. (Wasserman, 2012). Participants were asked to maintain a pedal rate of 60 revolutions per minute (rpm) and the test was terminated when they reached their self-determined point of full exhaustion or were unable to maintain the required pedal rate despite strong verbal encouragement. Echocardiographic measurements were reviewed and the residual doppler gradient (continuous wave) over the aortic coarctation zone at rest (mmHg) was defined.

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