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The concentration−response curves were generated and EC50/CC50 values were calculated using OriginPro software (OriginLab, Northampton, MA). Statistical analyses were performed using Prism (GraphPad Software, La Jolla, CA) by one-way ANOVA with posthoc Bonferroni test for multiple comparisons. P < 0.05 was considered statistically significant. All data are presented as mean + or ± SEM.
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