Cells were transfected with small interfering RNA (siRNA) duplexes using Lipofectamine 2000 (Thermo Fisher Scientific, Waltham, MA, USA) according to the manufacturer's instructions. siRNA with the following sequences were obtained from GenePharma (Shanghai, China): siSTAT3#1, 5′‐CCA CUU UGG UGU UUC AUA A‐3′; siSTAT3#2, 5′‐GGA GAA GCA UCG UGA GUG A‐3′; siLIFR#1, 5′‐CCA CAC CGC UCA AAU GUU A‐3′; siLIFR#2, 5′‐GAA CAA AAC GUU UCC UUA A‐3′.
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