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Binary Prediction Analysis and ROC Evaluation
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The diagnostic utility of all MCTD-DMS was evaluated by performing logistic regression analyses and calculating the AUC curve in both our discovery and replication sample using the pROC R package. We performed logistic regression models to find out how well epigenetic markers differentiate MCTD from the healthy population and also from every other SADs included in this study. The covariates used in the logistic models were the same as previously explained for linear models.
Copyright and License information: ©2019 Carnero-Montoro, Barturen, Povedano, Kerick, Martinez-Bueno, PRECISESADS Clinical Consortium, Ballestar, Martin, Teruel and Alarcón-Riquelme.
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
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