2.1. Sample

Sixty-six patients were selected at a memory clinic at the Hospital Universitario San Ignacio: 20 svPPA (mean age 60.3 ±7.65, 20 nfvPPA (mean age 63.63 ±6.87), 26 bvFTD (mean age 64.38 ±5.72) and, 33 healthy controls (mean age 61.3 ±7.22) (see Table 1). Patient fulfilled the Lund and Manchester criteria (27) the revised criteria for probable bvFTD (28) and, criteria for the 3 variants of PPA—nonfluent/agrammatic, semantic, and logopenic (4). All patients had Spanish as their primary language and had an informant. All patients were diagnosed and classified in the memory clinic by a multidisciplinary team focused on neurology, neuropsychology, geriatrics, and psychiatry. Healthy controls were excluded if they had a history of psychiatry or neurological illness, substance abuse, and other causes of brain damage. This study was approved by the ethical committee of the Hospital Universitario San Ignacio/Pontificia Universidad Javeriana and all participants signed the informed consent form.

Demographic, clinical, and cognitive data from patients with controls, svPPA, nfvPPA, and bvFTD.

The numbers are the mean and standard deviation, svPPA, semantic variant PPA; nfvPPA, non-fluent variant; bvFTD, behavioral variant FTD; FIB, Frontal behavioral inventory; CUSPA, Columbia University Scale for Psychopathology in Alzheimer's Disease; RFC, Rey figure copy; SS, spontaneous speech.