All the statistical analysis was performed using SPSS version 21.0 (SPSS Inc., Chicago Illinois, USA). Continuous variables with normal distribution were presented as mean ± SD and median (Q1–Q3 quartiles) represented continuous but with non-normal distribution variables. Categorical variables were presented as number (percentage). To compare the differences among groups, continuous parameters were analyzed with Student’ s t-test, analysis of variance (ANOVA) or Mann-Whitney U test. Categorical variables were analyzed using chi-square test and Fisher’s exact test if applicable. A p-value < 0.05 was considered significantly different.
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