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All animals except healthy control group rats were allowed free access to normal rat diet and the rats were be injected intraperitoneally with streptozotocin (STZ) (45 mg/kg). Blood glucose, was estimated 7 days after the STZ injection. The rats with blood glucose of ≥200 mg/dl, was considered diabetic rats and selected for further pharmacological studies. These rats were randomly allocated to various experimental groups and fed test drug orally using a feeding cannula for next 30 days.
Copyright and License information: ©2016 Journal of Clinical and Diagnostic Research
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