β-Arrestin assay

C. Ämmälä
WI W. J. Drury, III
LK L. Knerr
IA I. Ahlstedt
PS P. Stillemark-Billton
CW C. Wennberg-Huldt
EA E.-M. Andersson
EV E. Valeur
RJ R. Jansson-Löfmark
DJ D. Janzén
LS L. Sundström
JM J. Meuller
JC J. Claesson
PA P. Andersson
CJ C. Johansson
RL R. G. Lee
TP T. P. Prakash
PS P. P. Seth
BM B. P. Monia
SA S. Andersson
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β-Arrestin recruitment was measured in Chinese hamster ovary (CHO) K1 hGLP1R β-arrestin2 (DiscoverX, #93-0300C2) cells after 90 min incubation with compounds in Ham’s F-12, 1% FBS, and 0.3% DMSO at 37°C according to the manufacturer’s PathHunter assay protocol (DiscoverX Corporation, Fremont, CA).

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