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Biopsy and definition of AS recurrence

AK Ai Katsuma
YN Yasuyuki Nakada
IY Izumi Yamamoto
SH Shigeru Horita
MF Miyuki Furusawa
KU Kohei Unagami
HK Haruki Katsumata
MO Masayoshi Okumi
HI Hideki Ishida
TY Takashi Yokoo
KT Kazunari Tanabe
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Graft biopsy was performed based on episodic hematuria and proteinuria or worsening renal function. The other protocol biopsies were performed at 3 months, 1 year, and 3 years after kidney transplantation. We defined the recurrence of AS as either focal or diffuse defects of immunoreactivities of type IV collagen α5 chains in the GBM. On electron microscopy, we defined the recurrence of AS as the significant progression of irregular thinning and thickening of the GBM with splitting and lamellation of the lamina densa.

Copyright and License information: The Author(s). ©2018
Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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