2.3. Groups

Thirty rats were randomly separated into 5 groups:

Sham group: six rats were treated with opening the renal capsule and exposing the kidney for 5 min, then sutured the muscle layer and skin. After one week, the same amount of normal saline per day was intraperitoneally injected

Model group: six uremic rat models were established through 5/6 nephrectomy. After one week, the rats were treated with intraperitoneal injection of the same amount of normal saline per day

Low dose of resveratrol (Res-L) group: six uremic rat models were established through 5/6 nephrectomy, and after one week, 5 mg/kg resveratrol (suspended in 0.5% sodium carboxymethylcellulose) was intraperitoneally administered per day for 28 days

Medium dose of resveratrol (Res-M) group: six uremic rat models were established through 5/6 nephrectomy, and after one week, 10 mg/kg resveratrol (suspended in 0.5% sodium carboxymethylcellulose) was intraperitoneally administered per day for 28 days

High dose of resveratrol (Res-H) group: six uremic rat models were established through 5/6 nephrectomy, and after one week, 20 mg/kg resveratrol (suspended in 0.5% sodium carboxymethylcellulose) was intraperitoneally administered per day for 28 days