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Human myocardial tissue

SP Steffen Pabel
SA Shakil Ahmad
PT Petros Tirilomis
TS Thea Stehle
JM Julian Mustroph
MK Maria Knierim
ND Nataliya Dybkova
PB Philipp Bengel
AH Andreas Holzamer
MH Michael Hilker
KS Katrin Streckfuss-Bömeke
GH Gerd Hasenfuss
LM Lars S. Maier
SS Samuel Sossalla
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All procedures were performed according to the Declaration of Helsinki and were approved by the local ethics committee. Informed consent was obtained from all patients. Human atrial myocardium from patients with sinus rhythm or atrial fibrillation was acquired from atrial resections during open heart surgery (for patient characteristics, see Table ​Table1).1). For molecular purposes, we utilized left ventricular myocardium from healthy donor hearts that were not transplanted due to technical reasons.

Clinical characteristics of patients with sinus rhythm (n = 34) and patients with atrial fibrillation (n = 10)

Values are mean ± SEM or n (%). Clinical data could not be completely obtained from every patient

EF ejection fraction, ACE angiotensin-converting enzyme, PDE phosphodiesterase

aBlinded due to ethical reasons

Copyright and License information: The Author(s) ©2020
Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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