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2.2. Induction of Visceral Hypersensitivity
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The experimental animal model of IBS with visceral hypersensitivity was induced by neonatal colonic inflammation as previously described [34]. In brief, ten-day-old pups were administered an infusion of 0.2 ml of 0.5% acetic acid solution in saline into the colon 2 cm from the anus, only once. Control rats received an equal volume of normal saline. EA treatments were performed in the seventh week.
Copyright and License information: ©2020 Jingming Zhao et al.
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