2.4. Monitoring of renal function in NAFLD+HTN+ cases with CKD

The rate of decline of renal function was evaluated by the slope of reciprocal serum creatinine (SRSC) every 6 months within 24 months before and after included in this study (Figure ​(Figure2A).2A). Then, 39 enrolled cases with SKD were further sub-classified into CKD stable and CKD progression groups according to the changes of SRSC. CKD stable cases was defined as a slope of the regression line of less than −0.001 (dl mg⁻¹ month⁻¹) and the CKD progression cases were those with a slope of the regression line of more than −0.001 (dl mg⁻¹ month⁻¹). We compared the 2 groups with regards to clinical and laboratory parameters as the start of follow-up.