We identified the closest TSS to each cCRE-ELS using bedtools closest and GENCODE V19 TSS annotations. We compared two options: use of the full set of GENCODE TSSs (with problematic annotations removed) or use of only protein-coding GENCODE TSSs. To evaluate performance, we calculated the overall precision and recall for each BENGI dataset (Script: Closest-Gene-Method.sh).
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