4.4. Animal Behavioral Test

Following establishment of the cerebral ischemia reperfusion model, the behavioral scores were obtained using modified Bederson scores, as previously described [30]. The specific scoring criteria were as follows: 0, no deficit; 1, forelimb flexion deficit on the contralateral side; 2, decreased resistance to lateral push and torso turning to the ipsilateral side when held by the tail; 3, significant circling and reduced capability to bear weight on the affected side; and 4, animal rarely moving spontaneously.