The sequence of the putative CODH (F7O84_RS11645) was blasted with the BLASTp (version 2.2.28+; Altschul et al., 1997) tool of the JGI-IMG/M database (Markowitz et al., 2012), with default parameter settings. Finished genomes from members of the Lachnospiraceae family in the public JGI-IMG/M database (Markowitz et al., 2012) were selected for analysis, Supplementary Table S4. The stains identified in the BLAST search, or closely related strains (Supplementary Table S5) were subsequently analyzed in KEGG (Kanehisa et al., 2014) for presences of the CODH/ACS complex with pathway map 1200.
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