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Differentially expressed genes were determined using the Student’s t-test with false discovery rate multiple testing correction (FDR). The median-based fold changes (MBFC) were calculated to evaluate the ratio of expression changes between the studied groups. A gene with MBFC > 2 or MBFC < 0.5 and FDR < 0.2 (adequate to Student’s t-test p value < 0.05) was considered significantly differentially expressed.
Copyright and License information: ©2019 by the authors.
Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
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