We downloaded the series matrix files of datasets from GEO. The R package “limma” [41] was utilized to normalize the data and find DEGs. We then used RRA to integrate the results of those 10 datasets to find the most significant DEGs [11]. The P value of each gene indicated its ranking in the final gene list, and genes with adjusted P < 0.05 were considered as significant DEGs in the RRA analysis.
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