RESULTS

We collected the clinical data of patients with AP who visited our department from January 1, 2014 to December 31, 2018. A total of 205 NP patients were enrolled according to the results of enhanced CT in our hospital or another hospital. There were 140 males and 65 females, with an average age of 49.5 ± 15.7 years. The causes of NP were gallstones in 109 patients, hyperlipidemia in 67 patients, unknown etiology in 12 patients, alcoholism in 10 patients, endoscopic retrograde cholangio-pancreatography in 6 patients, and posttraumatic pancreatitis in 1 patient. There was no significant difference in age, sex, or etiology between the infection group and the non-infection group (Table ​(Table11).

Comparison of baseline demographic and clinical characteristics between the infection group and non-infection group

Among the 205 NP patients, 163 had infectious complications, and 42 had sterile necrosis. The different degrees of pancreatic necrosis in the patients with NP were as follows: 40 (26/14) patients with less than 30% necrosis, 80 (65/15) with 30%-50% necrosis, and 85 (72/13) with more than 50% necrosis. The median modified computer tomography severity scan (CTSI) score was 4 (range, 0-10). There was a significant difference in the degree of necrosis between the infection group and the non-infection group (Table ​(Table11).

Among the 205 NP patients, 179 were referred, with a median referral time of 24 d; 150 had infectious complications and 29 had aseptic NP. There was no significant difference in the referral time between the infection group and the non-infection group (Table ​(Table11).