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Anti-inflammatory treatment with meloxicam.
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Two independent cohorts of KATP-GOF mice were treated with vehicle or meloxicam for 7 days, beginning 1 day before the 6-day tamoxifen and glibenclamide injection. Twenty-four KATP-GOF mice were treated with meloxicam (20 mg/g body wt) and 17 with vehicle (DMSO, 1 µl/g body wt). Blood glucose was followed over time, and pyruvate tolerance test was performed at day 0 (before treatment) and at day 7 after meloxicam/vehicle treatment.
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