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Biomarker Identification and Metabolic Pathway Analysis

CL Chun-Yu Li
CT Can Tu
DG Dan Gao
RW Rui-Lin Wang
HZ Hai-Zhu Zhang
MN Ming Niu
RL Rui-Yu Li
CZ Cong-En Zhang
RL Rui-Sheng Li
XX Xiao-He Xiao
MY Mei-Hua Yang
JW Jia-Bo Wang
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Compounds were selected as potential biomarkers with significant changes among groups (p-value < 0.05 and folder change > 1.5). They were identified by Agilent MassHunter PCDL Manager software, with KEGG1 database. To further identify the metabolic pathways, the pathway analysis of potential biomarkers was executed with MetaboAnalyst 3.02 on the basis of the te pathway library of Rattus norvegicus (rat). When the test p value is less than 0.05, statistical differences are considered significant.

Copyright and License information:  ©2016 Li, Tu, Gao, Wang, Zhang, Niu, Li, Zhang, Li, Xiao, Yang and Wang.
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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