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Tumor growth monitoring and survival time

RH Reihaneh Haghniaz
RU Rinku D Umrani
KP Kishore M Paknikar
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Tumor volumes in experimental mice (from subset I) were measured every alternate day from Day 0 to Day 14. Percent tumor growth inhibition (Tin) on Day 14 was calculated using the following formula:

Data are presented as mean ± standard error of the mean. Statistical analysis was performed by one-way analysis of variance followed by Dunnett’s multiple comparison test where P<0.05 was considered as minimal level of significance.

All experimental mice (of subset I) were not sacrificed and observed until mortality. Based on these observations, Kaplan–Meier survival curves were generated using GraphPad Prism software (version 5; GraphPad Software Incorporation, La Jolla, CA, USA). Statistical significance was analyzed by log rank test where a value of P<0.05 was considered as the minimal level of significance. Percent increase in life expectancy was calculated as follows:

Copyright and License information:  ©2016 Haghniaz et al. This work is published and licensed by Dove Medical Press Limited
The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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