Subjects

This prospective study was conducted from May 8, 2009 to June 13, 2011. It was approved by the institutional review board, and informed consent was obtained from all the subjects. Thirty-six patients diagnosed with primary glioma (WHO grade II to IV) were included in this study. One patient for whom perfusion imaging was not conducted was excluded. Finally, 35 patients (17 men and 18 women) were selected to participate in this study. The mean age of the men and women was 59.8 (range 23–91) and 45.9 (range 8–74) years, respectively. Nine, eight, and 18 patients were diagnosed to have grade II, III, and IV gliomas based on histological specimens, respectively (Table 1).

Characteristics of patients