Sequence analysis of antibody epitope conservation

CS Chenguang Shen
MZ Minwei Zhang
YC Yuanzhi Chen
LZ Limin Zhang
GW Guosong Wang
JC Junyu Chen
SC Siyuan Chen
ZL Zizhen Li
FW Feixue Wei
JC Jing Chen
KY Kunyu Yang
SG Shuxin Guo
YW Yujing Wang
QZ Qingbing Zheng
HY Hai Yu
WL Wenxin Luo
JZ Jun Zhang
HC Honglin Chen
YC Yixin Chen
NX Ningshao Xia
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A total of 2,000 full-length, non-redundant influenza B HA sequences were downloaded from the NCBI FLU database 55. All 2,000 sequences were aligned and analyzed using BIOEDIT software. In this analysis, a residue was considered conserved only if it was the same between two sequences. The values reported for percent conservation are the number of sequences with an identical residue at a position divided by the total number of sequences.

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