Gene Interval Notator [GIN, (37)] was used to annotate peaks over Refseq mouse genes. Promoters were defined as 6 kb regions (±3 kb) surrounding the transcriptional start site (TSS). A peak was generated by the TSS of a Refseq gene that falling into the surrounding 6 kb (±3 kb). Datasets are available for download from NCBI’s Gene Expression Omnibus (GEO, http://www.ncbi.nlm.nih.gov/geo). ChIP-Seq data and relative negative controls were download according to the GEO accession numbers that listed in Table S2.
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