TCGA data comparison with OncomineTM and survival time analysis with Oncolnc

LW Lian Wang
ZS Zhouchun Shang
YZ Yang Zhou
XH Xinyu Hu
YC Yihong Chen
YF Yantao Fan
XW Xiaoyu Wei
LW Liang Wu
QL Qiujuan Liang
JZ Jun Zhang
ZG Zhengliang Gao
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To further validate our results, we subjected the DEGs from our analyses to query the TCGA database through OncomineTM platform (Thermo. Fisher, Ann Arbor, MI; http://www.oncomine.org) by setting up the following parameters: “Cancer vs Normal analysis” and “Glioblastoma” options (547 GBM patient brain tissues versus 10 normal brain tissues). For survival analysis, Oncolnc platform was used to extract the prognostic value of DEGs on the survival time of 152 glioblastoma patients from TCGA database65. For each DEG, the 152 patients were arbitrarily divided as 76 patients with high expression versus 76 patients with low expression according to their expression level of the DEGs.

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