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Rats received a subplantar injection of 100 μl of a 1% (w/v) suspension of carrageenan lambda in the right hind paw [18]. The volume of the paw was measured by Plethysmometer (Ugo Basile, Italy) immediately before and then, 4 h after the carrageenan injection. Data were expressed as the increase in paw volume (ml) and compared with control values.
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