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Minimal Inhibitory Concentration Determination of M. tuberculosis Isolates

IR Ivy Rukasha
HS Halima M. Said
SO Shaheed V. Omar
HK Hendrik Koornhof
AD Andries W. Dreyer
AM Alfred Musekiwa
HM Harry Moultrie
AH Anwar A. Hoosen
GK Gilla Kaplan
DF Dorothy Fallows
NI Nazir Ismail
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Minimum inhibitory concentrations were determined using a commercially available Sensititre MYCOTB plate (TREK Diagnostics, Cleveland, OH, USA), following the manufacturer’s instructions. The MIC test range for both RIF and RFB was from 0.12 to 16 mg/L. Resistance and sensitivity to RIF were defined as MIC > 1 and MIC ≤ 1 mg/L, respectively, and to RFB as MIC > 0.5 and MIC ≤ 0.5 mg/L, respectively, based on laboratory standards (CLSI, 2011).

Copyright and License information:  ©2016 Rukasha, Said, Omar, Koornhof, Dreyer, Musekiwa, Moultrie, Hoosen, Kaplan, Fallows and Ismail.
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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