Measurement of Infiltration Depth of Local Tumor Cells

There were three main manifestations on pathological sections.

The boundary of GCTB was irregular. There were scattered GCTB tumor cells infiltrated in the surrounding normal tissues. In this visual field, point a and point b were the positions of the innermost boundary, respectively. The connection line between the two points was defined as the innermost boundary (segment ab). Point c was the farthest infiltrating tumor cell in the field of vision. The length of the vertical line (segment cd) between the farthest local infiltration cell and segment ab was defined as the depth of tumor cell infiltration (Fig. ​(Fig.11A).

(A) Segment ab was the line connecting the innermost boundary of the tumor and point c was the farthest infiltrating tumor cell in the field of vision. The length of segment cd which was perpendicular to line ab was the farthest infiltrating depth of tumor cells. (B) Segment ab was the connection between two broken ends of the tumor boundary. Point c was the farthest infiltrating tumor cell in the field of vision. The segment cd length which was perpendicular to segment ab was defined as the farthest infiltrating depth. (C) the boundary was clear and continuous. There was no obvious local infiltration of tumor cells into the surrounding normal tissues.

The boundary of GCTB was irregular with GCTB tumor cells locally infiltrating into normal tissues. Point a and point b were the two broken ends of the boundary, respectively. The connection line between the two points was defined as the boundary of GCTB. Point c was the farthest infiltrating tumor cell. The length of the vertical line (segment cd) between the farthest local infiltration cell and segment ab was defined as the depth of tumor infiltration (Fig. ​(Fig.11B).

The boundary of GCTB tumors was clear and continuous. There was no obvious local infiltration of tumor cells into the surrounding normal tissues. We believed that there was no obvious local tumor cell infiltration (Fig ​(Fig11C).