Exclusion Criteria

Patients were excluded if they were employed by a pharmaceutical company or marketing agency, or if they were employed by an unsuitable entity, such as the government or a pharmacy, as such occupations may have biased their responses to research based on survey data. Patients were also precluded from taking part in the survey if they were younger than 18 years (all countries but the United States) or 25 years (United States only) (see Supplementary Appendix B, Patient Questionnaire).

Similar to patients, HCPs were excluded from participation in the survey if they were employed by a pharmaceutical or market research company, or if (in the United States only) they or an immediate family member was employed by an unsuitable agency, such as the FDA (see Supplementary Appendix C, HCP Questionnaire).

Patients and HCPs were excluded if they discontinued the survey for any reason. Finally, patients and HCPs were removed from the final sample if they were deemed to have 1) provided their answers to a series of questions in the same place on a rating scale, 2) completed the study in an unrealistically short time (i.e., less than 40% of the mean time taken by patients and HCPs), or 3) provided nonsensical open-ended responses.