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The study was an open-label clinical trial with a sequential enrolment of patients treated with AL or AS–AQ. After 50 children were treated with AL, another 50 children received AS–AQ. The primary objective was to assess the PCR corrected cure rates at day 28; the secondary objectives were to assess patterns of fever and parasite clearance; changes in haemoglobin levels after treatment by AL or AS–AQ as well as their safety and tolerability; and investigate the presence of artemisinin resistance molecular markers.
Copyright and License information: The Author(s) ©2019
Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
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