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Hemospon® fragments, a lyophilized and hydrolyzed collagen sponge with porcine origin (Technew, Rio de Janeiro, RJ, Brazil), which had a size that was compatible with the size of the bone defect (2 mm/2 mm), were obtained. The fragments remained immersed in 2 mL of the culture medium in an incubator with 5% CO2 at 37°C, for 24 hours before the surgical procedures. For groups 4 and 5, we used a culture medium containing 106 cells/mL.
Copyright and License information: ©2019
This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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