All animal procedures were performed following the recommendations of the Uruguayan National Commission of Animal Experimentation (CNEA), approved experimental protocol 001/02/2012 (code: 008/11; http://www.cnea.org.uy/index.php/instituciones/registro/10). Animals were euthanized by cervical dislocation, in accordance with the National Law of Animal Experimentation 18,611 (Uruguay).
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