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RM Ramona Miske
CG Catharina C. Gross
MS Madeleine Scharf
KG Kristin S. Golombeck
MH Marvin Hartwig
UB Urvashi Bhatia
AS Andreas Schulte-Mecklenbeck
KB Kathrin Bönte
CS Christine Strippel
LS Ludger Schöls
MS Matthis Synofzik
HL Hubertus Lohmann
ID Inga Madeleine Dettmann
MD Michael Deppe
SM Swantje Mindorf
TW Tobias Warnecke
YD Yvonne Denno
BT Bianca Teegen
CP Christian Probst
SB Stefanie Brakopp
KW Klaus-Peter Wandinger
HW Heinz Wiendl
WS Winfried Stöcker
SM Sven G. Meuth
LK Lars Komorowski
NM Nico Melzer
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All patients were assessed clinically by experienced neurologists (K.S.G., C.S., T.W., N.M.). Cerebellar dysfunction was rated using the Scale for the Assessment and Rating of Ataxia (SARA)16 and documented by videography following written informed consent of the patients.

Control collectives included 37 healthy donors, 33 patients with neurologic symptoms and defined antineural autoantibodies (5× anti-NMDAR, 5× anti-Hu, 2× anti-Hu/anti-Ri, 3× anti-Yo, 2× anti-Yo/anti-Ri, 3× anti-Ri, 5× anti-AQP4, 5× anti-LGI1, 3× anti-CASPR2), 36 treatment-naive patients with relapsing-remitting multiple sclerosis (RRMS), 20 patients with the cerebellar type of multiple system atrophy (MSA-c), 35 patients with hereditary cerebellar ataxias, and 150 consecutive patients with various neurologic disorders collected from all participating neurologic departments.

Details on neuropsychological assessment and quantitative high-resolution structural MRI can be found in the e-Methods at Neurology.org/nn.

Copyright and License information:  ©2016 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology
This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License 4.0 (CC BY-NC-ND), which permits downloading and sharing the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.

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