Validation and prognostic significance analysis of the hub genes

LG Lihuang Guo
ML Mingyue Lin
ZC Zhenbo Cheng
YC Yi Chen
YH Yue Huang
KX Keqian Xu
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The expressions of hub genes were compared among different nodal metastasis status of PCa using UALCAN, an interactive web portal to analyze The Cancer Genome Atlas (TCGA) gene expression data deeply (Chandrashekar et al., 2017). The PCa samples were divided into three groups (metastases in lymph nodes vs no regional lymph node metastasis vs normal). Then the prognostic significance of each hub gene was performed by gene expression profiling interactive analysis (GEPIA) (Tang et al., 2017). P < 0.05 was considered to indicate a statistically significant difference.

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