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2.13. Transcription Factor Enrichment (TFE)

AZ Alfeu Zanotto-Filho
SR Subapriya Rajamanickam
EL Eva Loranc
PM Pragathi Masamsetti
AG Aparna Gorthi
JR July Carolina Romero
ST Sonal Tonapi
RG Rosangela Mayer Gonçalves
RR Robert L. Reddick
RB Raymond Benavides
JK John Kuhn
YC Yidong Chen
AB Alexander J. R. Bishop
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TFE was performed using the ChIP Enrichment Analysis (ChEA, 2015 release) available with the Enrichr bioinformatics tool (http://amp.pharm.mssm.edu/Enrichr/enrich) (20). From an input gene list of MMS/sorafenib DEG, the ChEA program computes over-representation of transcription factor targets based on shared overlapping targets and binding site proximity from the ChIP-x (CheA) database.

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