2.5. Risk of bias in individual studies

We assessed the quality of the individual study using the Cochrane collaboration’s tool for determining the risk of bias in randomized trials [24]. These are summarized in Table 1 and Supplementary Figure 1.

Cochrane risk of bias for quality assessment.

RCT = Randomized Control Trial, NEJM = New England Journal of Medicine, JACC = Journal of American College of Cardiology, NVAF = Non-Valvular Atrial Fibrillation, SAPT = Clopidogrel or Ticagrelor, DAPT = Clopidogrel or Ticagrelor + Aspirin, LD = Low Dose, VLD = Very Low Dose

Characteristics and differences of RCT’s.

RCT = Randomized Control Trial, NEJM = New England Journal of Medicine, JACC = Journal of American College of Cardiology, NVAF = Non-Valvular Atrial Fibrillation, OAC = Oral Anti-Coagulation, DES = Drug Eluting Stent, ACS = Acute Coronary Syndrome, SAPT = Single Anti-Platelet Therapy (Clopidogrel or Ticagrelor), DAPT = Dual Anti-Platelet Therapy (Clopidogrel or Ticagrelor + Aspirin), LD = Low Dose, VLD = Very Low Dose, TIMI = Thrombolysis in Myocardial Infarction, MI = Myocardial Infarction.