Patients

From January 2016 to January 2018, 76 patients with gastric cancer were enrolled in Cancer Hospital of China Medical University to serve as research subjects. Inclusion criteria: 1) gastric cancer patients confirmed by histopathological examinations; 2) no history of malignancies. Exclusion criteria: 1) patients with other medical conditions besides gastric cancer; 2) patients who were transferred from other hospital or had been treated within 3 months before admission. The 76 patients included 39 males and 37 females, and age ranged from 32 to 69 years, and the mean age was 51.2±8.1 years. According to AJCC staging, there were 18, 18, 20 and 20 cases at stage 1-IV, respectively. This study was approved by Ethics Committee of Cancer Hospital of China Medical University. All procedures performed in studies involving human participants were conducted in accordance with the Declaration of Helsinki. All patients provided written form informed consent.