Evidence on GEP-NET and Management Options: MCDA Evidence Matrices

An evidence matrix was created following EVIDEM’s targeted systematic literature review methodology and data synthesis approach as reported previously [12, 13]. It was updated and adapted to the Spanish context, and translated into Spanish. Briefly, relevant evidence was retrieved from the biomedical literature databases (PubMed/Medline), Cochrane systematic reviews, clinical trial registries, conferences, bibliographies of pertinent publications, and patient and professional association websites (as well as other gray literature and proprietary data, as applicable). Clinical data were validated by a Spanish clinical GEP-NET expert. The evidence matrices included a total of 36 references.