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MB Marie T Borin
AL Arthur Lo
CB Chris N Barnes
SP Srikanth Pendyala
DB David L Bourdet
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Both studies were open-label. Study treatment and restrictions on concomitant medications were the same for both studies. All subjects received a single dose of revefenacin (175 µg) administered as a 3-mL solution by inhalation using the PARI LC® Sprint (PARI, Midlothian, VA, USA) jet nebulizer. Subjects were prohibited from using nephrotoxic or hepatotoxic medications for 4 weeks before study drug dosing. Permitted medications included acetaminophen, ibuprofen, milk of magnesia (magnesium hydroxide), and routine vitamins and minerals. In addition, subjects could continue a stable regimen of any medication (except those specifically prohibited) in place 30 days before day –1.

Copyright and License information:  ©2019 Borin et al.
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