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Statistics were calculated using Prism (GraphPad v5.0) and SPSS (IBM, v21.0). Error bars indicate the standard error of the mean (SEM). One-way ANOVA was used to examine the significant differences in the experimental data between the groups. P values were indicated in each figures: * P < 0.05, **P < 0.01, *** P < 0.001. P < 0.05 was regarded as significant. All experiments were independently repeated three times.
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Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
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