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Poly(lactic-co-glycolic acid) (PLGA) and silymarin (purity > 98%) were purchased from Dalian Meilun Biotechnology Co. Ltd (Dalian, China). Chitosan (75–85% deacetylation, 20–300 cP, mol. wt. 50–190 kDa) and coumarin-6 were purchased from Sigma Aldrich (St. Louis, MO). 1,2-distearoyl-sn-glycero-3-phosphoethanol-amine-N-methoxy (polyethylene glycol)-2000 (DSPE-PEG2000) was purchased from A.V.T. Pharmaceutical Co. Ltd (Shanghai, China). Caco-2 cells and HepG2 cells were from Shanghai Institutes for Biological Sciences (Shanghai, China).
Copyright and License information: The Author(s) ©2018
Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
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