CNE2-EBV−/+ and TWO3-EBV−/+ cells were treated with 0.1% DMSO or 1 μM JQ1 for 3 h, and mRNA was extracted using an AllPure Cell Kit (Magen, Guangzhou, China) according to the manufacturer’s instructions and submitted to Beijing Novogene Bioinformatics Technology Company Limited for RNA-seq analysis. Analysis of RNA-seq data and gene set enrichment analysis (GSEA) were performed by Guangzhou Genedenovo Bio-Technology Company Limited. A detailed description of the GSEA methodology is provided at http://www.broadinstitute.org/gsea/doc/GSEAUserGuideFrame.html.
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