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Modified Neurological Severity Score

XG Xin Guan
YW Yunjie Wang
GK Guoyin Kai
SZ Shunyi Zhao
TH Tingyu Huang
YL Youzhen Li
YX Yuan Xu
LZ Luyong Zhang
TP Tao Pang
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Modified neurological severity score is used mainly to determine the improvement of neurological deficit, thus we used this method to assess the neurological impairment of rats after tMCAO with or without the administration of CBL. The modified neurological severity score (mNSS) contains exercise test, tailing test, the placement test, proprioceptive test (deep sensation, pushing the paw against the table edge to stimulate limb muscles), balance beam test, the experiment of reflex loss and abnormal movement. The Maximum point is 18 and the overall points were assessed by the behavior of rats after tMCAO (normal score, 0; maximal deficit score, 18).

Copyright and License information:  ©2019 Guan, Wang, Kai, Zhao, Huang, Li, Xu, Zhang and Pang
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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